AG Linke
Lead:
Prof. Dr. Julia Linke
Research Group Leader LIR, Research group leader, Chair for Clinical Psychology and Neuroscience of Resilience (CPNR), Johannes-Gutenberg University, Mainz
Theresa Steffan, Wissenschaftsmanagerin | Kontakt: theresa.steffan@lir-mainz.de
Emil Stobbe, Postdoktorand | Kontakt: emil.stobbe@lir-mainz.de
Zeliha Sahintürk, Doktorandin | Kontakt: zeliha.sahintuerk@lir-mainz.de
Our research group aims to better understand the biological and psychological processes that promote resilience or maintain psychological distress. Building on this knowledge, we develop and evaluate accessible, scalable interventions to reach as many people as possible. We focus primarily on adolescents and young adults, as these developmental periods are particularly sensitive to stress but also offer important opportunities for prevention and change. Methodologically, our work integrates clinical and developmental psychology with modern cognitive neuroscience. We take an interdisciplinary, multimethod approach, combining large publicly available datasets with our own behavioral experiments and longitudinal studies, neuroimaging, psychophysiological measures, and assessments in everyday life. To analyze these data, we use advanced statistical methods, machine learning, and computational modeling.
- Development and evaluation of evidence-based, low-threshold, and scalable interventions to promote resilience
- Investigation of the role of internal world models as a resilience factor and a prevention target
- Modeling resilience in the context of disadvantage and discrimination
- Ilka Diester, Universität Freiburg, Deutschland
- Hanna Keren, Bar-Ilan University, Israel
- Daniel S. Pine, National Institute of Mental Health, USA
- Joel Stoddard, University of Colorado Denver, USA
- Anderson Winkler, University of Texas Rio Grande, USA
- DFG
- NIH
Linke JO, Naim R, Haller SP, Koshravi P, Scheinberg B, Byrne ME, Harrewijn A, Leibenluft E, Brotman MA, Winkler AM, Pine DS (2026) Reduced threat-related neural efficiency: a possible biomarker for pediatric anxiety disorders. Am J Psychiatry. doi.org/10.1176/appi.ajp.20241043
>> Link to articleBrown BS, Nguyen L, Morales I, Cardinale EM, Tseng W-L, McKay CC, Kircanski K, Brotman MA, Pine DS, Leibenluft E, Linke JO (2025) Associations between neighborhood resources and youth’s response to reward omission in a task modeling negatively biased environments. J Am Acad Child AdolescPsychiatry. doi.org/10.1016/j.jaac.2024.05.011
>> Link to articleXu EP, Stange JP, Linke JO (2025) Network analysis suggest working memory as a key target for facilitating subjective well-being. J Affect Disord. doi.org/10.1016/j.jad.2025.120139
>> Link to articleHaller SP, Linke JO, Grassie HL, Jones EL, Pagliaccio D, Harrewijn A, White LK, Naim R, Abend R, Mallidi A, Berman E, Lewis KM, Kircanski K, Fox NA, Silverman WK, Kalin NH, Bar-haim Y, Brotman MA (2024) Normalization of Fronto-Parietal Activation by Cognitive-Behavioral Therapy in Unmedicated Pediatric Patients With Anxiety Disorders. Am J Psychiatry. doi.org/10.1176/appi.ajp.20220449
>> Link to articleMcKay CC, Scheinberg B, Xu EP, Kircanski K, Pine DS, Brotman MA, Leibenluft E, Linke JO (2024) Modeling Shared and Specific Variances of Irritability, Inattention and Hyperactivity Yields Novel Insights Into White Matter Perturbations. J Am Acad Child Adolesc Psychiatry. doi.org/10.1016/j.jaac.2024.02.010
>> Link to articleLinke JO, Haller SP, Xu EP, Nguyen LT, Chue AE, Botz-Zapp C, Revzina O, Perlstein S, Ross AJ, Tseng W-L, Shaw P, Brotman MA, Pine DS, Gotts SJ, Leibenluft E, Kircanski K (2023) Persistent Frustration-Induced Reconfigurations of Brain Networks Predict Individual Differences in Irritability. J Am Acad Child Adolesc Psychiatry. 62(6):684–695. doi.org/10.1016/j.jaac.2022.11.009
>> Link to articleLinke JO, Abend R, Kircanski K, Clayton M, Stavish C, Benson B, Brotman MA, Renaud O, Smith SM, Nichols TE, Leibenluft E, Winkler A, Pine DS (2021) Shared and anxiety-specific pediatric psychopathology dimensions manifest distributed neural correlates. Biological Psychiatry. doi.org/10.1016/j.biopsych.2020.10.018
>> Link to article